TBCD anticorps

N° du produit ABIN7120359

Cet anticorps anti-TBCD est un anticorps Lapin Polyclonal détectant TBCD dans WB, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TBCD anticorps (ABIN7120359)

Antigène: TBCD (Tubulin Folding Cofactor D (TBCD))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBCD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-TBCD anticorps

Fonction: TBCD antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: tubulin folding cofactor D

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TBCD

Antigène: TBCD (Tubulin Folding Cofactor D (TBCD))

Autre désignation: TBCD

Sujet:

Synonyms: Tubulin-specific chaperone D|Beta-tubulin cofactor D (tfcD)|SSD-1|Tubulin-folding cofactor D|TBCD|KIAA0988|SSD1|TFCD

Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

Poids moléculaire: 130 kDa

ID gène: 6904

UniProt: Q9BTW9

Pathways: Cell-Cell Junction Organization