TNFAIP1 anticorps

N° du produit ABIN7120411

Cet anticorps Souris Monoclonal détecte spécifiquement TNFAIP1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour TNFAIP1 anticorps (ABIN7120411)

Antigène: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNFAIP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2H3

Détail du produit anti-TNFAIP1 anticorps

Fonction: TNFAIP1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: tumor necrosis factor, alpha-induced protein 1(endothelial)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:6000, IHC: 1:50-1:600

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TNFAIP1

Antigène: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Autre désignation: TNFAIP1

Sujet:

Synonyms: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2)|BTB/POZ domain-containing protein TNFAIP1|Protein B12|Tumor necrosis factor, alpha-induced protein 1, endothelial|TNFAIP1|BACURD2|EDP1

Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Poids moléculaire: 36 kDa

ID gène: 7126

UniProt: Q13829