U2AF1 anticorps
Aperçu rapide pour U2AF1 anticorps (ABIN7120448)
Antigène
Voir toutes U2AF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- U2AF1 antibody
-
Purification
- Protein A+G purification
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- U2 small nuclear RNA auxiliary factor 1
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))
-
Autre désignation
- U2AF1
-
Sujet
-
Synonyms: Splicing factor U2AF 35 kDa subunit|U2 auxiliary factor 35 kDa subunit|U2 small nuclear RNA auxiliary factor 1|U2 snRNP auxiliary factor small subunit|U2AF1|U2AF35|U2AFBP
Background: U2 auxiliary factor(U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2(RNU2) small nuclear RNA auxiliary factor 1(U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
-
Poids moléculaire
- 38 kDa
-
ID gène
- 7307
-
UniProt
- Q01081
Antigène
-