Urm1 anticorps

N° du produit ABIN7120488

Cet anticorps anti-Urm1 est un anticorps Lapin Polyclonal détectant Urm1 dans WB, ELISA et IHC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour Urm1 anticorps (ABIN7120488)

Antigène: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Urm1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Urm1 anticorps

Fonction: URM1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin related modifier 1 homolog

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC:1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Urm1

Antigène: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Autre désignation: URM1

Sujet:

Synonyms: Ubiquitin-related modifier 1|URM1|C9orf74

Background: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated(-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein(UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

Poids moléculaire: 11 kDa

ID gène: 81605

UniProt: Q9BTM9