USP1 anticorps

N° du produit ABIN7120489

Cet anticorps Lapin Polyclonal détecte spécifiquement USP1 dans WB, ELISA, IHC et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour USP1 anticorps (ABIN7120489)

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-USP1 anticorps

Fonction: USP1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IHC: 1:20-1:200,IP: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur USP1

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Autre désignation: USP1

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP)|Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1

Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).

Poids moléculaire: 100 kDa

ID gène: 7398

UniProt: O94782