USP1 anticorps (AA 430-785)

N° du produit ABIN7120490

L’anticorps Souris Monoclonal anti-USP1 a été validé pour WB, ELISA et IHC. Il convient pour détecter USP1 dans des échantillons de Humain.

Aperçu rapide pour USP1 anticorps (AA 430-785) (ABIN7120490)

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8F7

Détail du produit anti-USP1 anticorps

Épitope: AA 430-785

Fonction: USP1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 430-785aa

Immunogen: ubiquitin specific peptidase 1

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:10000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur USP1

Antigène: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Autre désignation: USP1

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP)|Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1

Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).

Poids moléculaire: 90 kDa

ID gène: 7398

UniProt: O94782