USP16 anticorps

N° du produit ABIN7120500

Cet anticorps anti-USP16 est un anticorps Lapin Polyclonal détectant USP16 dans WB, ELISA, IHC et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour USP16 anticorps (ABIN7120500)

Antigène: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-USP16 anticorps

Fonction: USP16 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 16

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur USP16

Antigène: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Autre désignation: USP16

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 16|Deubiquitinating enzyme 16|Ubiquitin thioesterase 16|Ubiquitin-processing protease UBP-M|Ubiquitin-specific-processing protease 16|USP16

Background: Specifically deubiquitinates 'Lys-120' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3(H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B-and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

Poids moléculaire: 94 kDa

ID gène: 10600

UniProt: Q9Y5T5