USP16 anticorps

N° du produit ABIN7120500

Détail du produit anti-USP16 anticorps

Antigène: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 16

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur USP16

Antigène: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Autre désignation: USP16 (USP16 Produits)

Synonymes: anticorps ubp-m, anticorps USP16, anticorps UBP-M, anticorps 1200004E02Rik, anticorps 2810483I07Rik, anticorps 6330514E22Rik, anticorps UBPM, anticorps si:ch211-238e22.5, anticorps si:dkey-121n8.2, anticorps wu:fc76b02, anticorps wu:fc76b08, anticorps universal stress protein, anticorps ubiquitin specific peptidase 16, anticorps ubiquitin specific peptidase 16 L homeolog, anticorps usp16, anticorps USP16, anticorps Usp16, anticorps usp16.L

Sujet: Synonyms:Deubiquitinating enzyme 16, Ubiquitin thiolesterase 16, UBP M, USP16 Background:Specifically deubiquitinates 'Lys-120' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3(H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B-and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.

Poids moléculaire: 94 kDa

ID gène: 10600

UniProt: Q9Y5T5