USP34 anticorps

N° du produit ABIN7120515

Cet anticorps anti-USP34 est un anticorps Lapin Polyclonal détectant USP34 dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour USP34 anticorps (ABIN7120515)

Antigène: USP34 (Ubiquitin Specific Peptidase 34 (USP34))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP34 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-USP34 anticorps

Fonction: USP34 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 34

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur USP34

Antigène: USP34 (Ubiquitin Specific Peptidase 34 (USP34))

Autre désignation: USP34

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 34|Deubiquitinating enzyme 34|Ubiquitin thioesterase 34|Ubiquitin-specific-processing protease 34|USP34|KIAA0570|KIAA0729

Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

Poids moléculaire: 47 kDa

ID gène: 9736

UniProt: Q70CQ2