UBE2K anticorps

N° du produit ABIN7120554

Détail du produit anti-UBE2K anticorps

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2K est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin-conjugating enzyme E2K

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur UBE2K

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Autre désignation: UBE2K (UBE2K Produits)

Synonymes: anticorps E2-25K, anticorps HIP2, anticorps HYPG, anticorps LIG, anticorps UBC1, anticorps E2-25k, anticorps Hip2, anticorps Hypg, anticorps Lig, anticorps e2-25k, anticorps hip2, anticorps hypg, anticorps lig, anticorps AW492011, anticorps D5Ertd601e, anticorps ube2k, anticorps zgc:103472, anticorps zgc:110791, anticorps ubiquitin conjugating enzyme E2 K, anticorps ubiquitin-conjugating enzyme E2K, anticorps ubiquitin conjugating enzyme E2 K S homeolog, anticorps ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast), anticorps ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast), anticorps UBE2K, anticorps Ube2k, anticorps ube2k.S, anticorps ube2k, anticorps ube2kb, anticorps ube2ka

Sujet: Synonyms:DKFZp564C1216, DKFZp686J24237, E2-25K, HIP 2, HIP2, HYPG, LIG, UBE2K, Ubiquitin carrier protein, Ubiquitin protein ligase Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation(ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.

Poids moléculaire: 25 kDa

ID gène: 3093

UniProt: P61086