UNC13A/Munc13-1 anticorps

N° du produit ABIN7120613

L’anticorps Lapin Polyclonal anti-UNC13A/Munc13-1 a été validé pour WB et ELISA. Il convient pour détecter UNC13A/Munc13-1 dans des échantillons de Humain et Souris.

Aperçu rapide pour UNC13A/Munc13-1 anticorps (ABIN7120613)

Antigène: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC13A/Munc13-1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UNC13A/Munc13-1 anticorps

Fonction: UNC13A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: unc-13 homolog A(C. elegans)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur UNC13A/Munc13-1

Antigène: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Autre désignation: UNC13A

Sujet:

Synonyms: Protein unc-13 homolog A|Munc13-1|UNC13A|KIAA1032

Background: UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.

Poids moléculaire: 193 kDa

ID gène: 23025

UniProt: Q9UPW8

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis