VTCN1 anticorps
Aperçu rapide pour VTCN1 anticorps (ABIN7120696)
Antigène
Voir toutes VTCN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- VTCN1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- V-set domain containing T cell activation inhibitor 1
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Isotype
- IgG
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Indications d'application
- WB: 1:200-1:2000, IHC: 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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Autre désignation
- VTCN1
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Sujet
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Synonyms: V-set domain-containing T-cell activation inhibitor 1|B7 homolog 4 (B7-H4)|B7h.5|Immune costimulatory protein B7-H4|Protein B7S1|T-cell costimulatory molecule B7x|VTCN1|B7H4
Background: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
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Poids moléculaire
- 50-80 kDa
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ID gène
- 79679
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UniProt
- Q7Z7D3
Antigène
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