Villin 1 anticorps

N° du produit ABIN7120768

Cet anticorps Souris Monoclonal détecte spécifiquement Villin 1 dans IHC, WB, IF, ELISA et IP. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Villin 1 anticorps (ABIN7120768)

Antigène: Villin 1 (VIL1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Clone: 3D11

Détail du produit anti-Villin 1 anticorps

Fonction: VIL1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: villin 1

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:50-1:2000, IF: 1:10-1:100, IP: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: VIL1

Sujet:

Synonyms: Villin-1|VIL1|VIL

Background: Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.

Poids moléculaire: 93 kDa

ID gène: 7429

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization