WDFY3 anticorps

N° du produit ABIN7120806

Cet anticorps anti-WDFY3 est un anticorps Lapin Polyclonal détectant WDFY3 dans ELISA et IHC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour WDFY3 anticorps (ABIN7120806)

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDFY3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-WDFY3 anticorps

Fonction: WDFY3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: WD repeat and FYVE domain containing 3

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur WDFY3

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Autre désignation: WDFY3

Sujet:

Synonyms: WD repeat and FYVE domain-containing protein 3|Autophagy-linked FYVE protein (Alfy)|WDFY3|KIAA0993

Background: Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

ID gène: 23001

UniProt: Q8IZQ1