WRAP53 anticorps

N° du produit ABIN7120809

Cet anticorps anti-WRAP53 est un anticorps Lapin Polyclonal détectant WRAP53 dans WB, IHC, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour WRAP53 anticorps (ABIN7120809)

Antigène: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WRAP53 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-WRAP53 anticorps

Fonction: WRAP53 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: WD repeat containing, antisense to TP53

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur WRAP53

Antigène: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Autre désignation: WRAP53

Sujet:

Synonyms: Telomerase Cajal body protein 1|WD repeat-containing protein 79|WD40 repeat-containing protein antisense to TP53 gene (WRAP53beta)|WRAP53|TCAB1|WDR79

Background: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.

Poids moléculaire: 72 kDa

ID gène: 55135

UniProt: Q9BUR4

Pathways: Telomere Maintenance