WT1 anticorps

N° du produit ABIN7120843

Cet anticorps Lapin Polyclonal détecte spécifiquement WT1 dans IHC, IF, WB, ELISA et IP. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour WT1 anticorps (ABIN7120843)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-WT1 anticorps

Fonction: WT1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Wilms tumor 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:50-1:500, IF: 1:20-1:200, IP: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1

Sujet:

Synonyms: Wilms tumor protein|WT33|WT1

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Poids moléculaire: 52 kDa

ID gène: 7490

UniProt: P19544

Pathways: Tube Formation