WTAP anticorps (AA 1-150)

N° du produit ABIN7120845

Cet anticorps anti-WTAP est un anticorps Souris Monoclonal détectant WTAP dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour WTAP anticorps (AA 1-150) (ABIN7120845)

Antigène: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WTAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 9D4

Détail du produit anti-WTAP anticorps

Épitope: AA 1-150

Fonction: WTAP antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-150aa

Immunogen: Wilms tumor 1 associated protein

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:10000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur WTAP

Antigène: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Autre désignation: WTAP

Sujet:

Synonyms: Pre-mRNA-splicing regulator WTAP|Female-lethal(2)D homolog (hFL(2)D)|WT1-associated protein|Wilms tumor 1-associating protein|WTAP|KIAA0105

Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).

Poids moléculaire: 49 kDa

ID gène: 9589

UniProt: Q15007