YTHDF1 anticorps (AA 133-349)

N° du produit ABIN7120903

Cet anticorps Lapin Polyclonal détecte spécifiquement YTHDF1 dans WB, ELISA, IHC et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour YTHDF1 anticorps (AA 133-349) (ABIN7120903)

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YTHDF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-YTHDF1 anticorps

Épitope: AA 133-349

Fonction: YTHDF1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 133-349aa

Immunogen: YTH domain family, member 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur YTHDF1

Antigène: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Autre désignation: YTHDF1

Sujet:

Synonyms: YTH domain-containing family protein 1 (DF1)|Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1)|YTHDF1|C20orf21

Background: Specifically recognizes and binds N6-methyladenosine(m6A)-containing mRNAs, and promotes mRNA translation efficiency(PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability(PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3(EIF3A or EIF3B) to facilitate translation initiation(PubMed:26046440).

Poids moléculaire: 62 kDa

ID gène: 54915

UniProt: Q9BYJ9