ZCCHC6 anticorps

N° du produit ABIN7121053

Cet anticorps Lapin Polyclonal détecte spécifiquement ZCCHC6 dans WB, IP et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ZCCHC6 anticorps (ABIN7121053)

Antigène: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZCCHC6 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Détail du produit anti-ZCCHC6 anticorps

Fonction: TUT7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: zinc finger, CCHC domain containing 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ZCCHC6

Antigène: ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))

Autre désignation: TUT7

Sujet:

Synonyms: Terminal uridylyltransferase 7 (TUTase 7)|Zinc finger CCHC domain-containing protein 6|TUT7|HS2|KIAA1711|ZCCHC6

Background: Uridylyltransferase that mediates the terminal uridylation of mRNAs with short(less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay(PubMed:19703396, PubMed:25480299). Involved in microRNA(miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets(PubMed:25480299). Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7(pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A(PubMed:22898984). Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.

Poids moléculaire: 171 kDa

ID gène: 79670

UniProt: Q5VYS8