ZW10 anticorps

N° du produit ABIN7121086

Cet anticorps Lapin Polyclonal détecte spécifiquement ZW10 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour ZW10 anticorps (ABIN7121086)

Antigène: ZW10 (Zw10 Kinetochore Protein (ZW10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZW10 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ZW10 anticorps

Fonction: ZW10 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ZW10, kinetochore associated, homolog(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ZW10

Antigène: ZW10 (Zw10 Kinetochore Protein (ZW10))

Autre désignation: ZW10

Sujet:

Synonyms: Centromere/kinetochore protein zw10 homolog|ZW10

Background: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER), the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).

Poids moléculaire: 90 kDa

ID gène: 9183

UniProt: O43264