MEF2B anticorps

N° du produit ABIN7504178

Détail du produit anti-MEF2B anticorps

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEF2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human MEF2B protein

Isotype: IgG2a

Information d'application

Indications d'application:

Positive Control: HeLa or Ramos cells.

Known Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur MEF2B

Antigène: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Autre désignation: MEF2B (MEF2B Produits)

Synonymes: anticorps si:ch211-125m10.1, anticorps AI451606, anticorps RSRFR2, anticorps myocyte enhancer factor 2b, anticorps myocyte enhancer factor 2B, anticorps mef2b, anticorps MEF2B, anticorps Mef2b

Sujet: MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, Myocyte enhancer factor 2B, Myocyte-specific enhancer factor 2B, PRDM3, RSRFR2, Serum response factor like protein 2, XMEF2,MEF2B (Transcriptional Activator)
Cellular localisation: Nucleus.

Poids moléculaire: 160kDa

ID gène: 100271849, 4207, 153629

UniProt: Q02080