TOM1L1 anticorps

N° du produit ABIN7504136

Détail du produit anti-TOM1L1 anticorps

Antigène: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TOM1L1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human TOM1L1 protein

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: Human kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur TOM1L1

Antigène: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Autre désignation: TOM1L1 (TOM1L1 Produits)

Synonymes: anticorps MGC52738, anticorps srcasm, anticorps TOM1L1, anticorps OK/KNS-CL.3, anticorps SRCASM, anticorps RGD1562626, anticorps Srcasm, anticorps 2310045L10Rik, anticorps C80573, anticorps target of myb1 like 1 membrane trafficking protein L homeolog, anticorps target of myb1 like 1 membrane trafficking protein, anticorps target of myb1-like 1 (chicken), anticorps tom1l1.L, anticorps TOM1L1, anticorps tom1l1, anticorps Tom1l1

Sujet: 2310045L10Rik, C80573, OK/KNS CL.3, Src activating and signaling molecule, SRCASM, Target of Myb like protein 1, Target of myb1 (chicken) homolog like 1, Target of myb1 (chicken) like 1, TOM1 like protein 1, TOM1L1 protein,TOM1L1 (Target of Myb1 Like 1 Membrane Trafficking Protein)
Cellular localisation: Golgi apparatus > Golgi stack. Endosome membrane.

Poids moléculaire: 53kDa.

ID gène: 10040, 153504

UniProt: O75674