FTCD anticorps

N° du produit ABIN7504162

Détail du produit anti-FTCD anticorps

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTCD est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: The antibody recognizes an epitope located on the microtubule-binding peripheral Golgi membrane 58 kDa protein. It is also useful for studies on the effect of microtubule-perturbing agents on the Golgi apparatus.The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively-spliced transcript variants have been found for this gene. Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi.

Réactivité croisée (Details): Human. Predicted to react in Mouse, Rat, Bovine, Dog, Hamster, Pig, Monkey and Kangaroo rat.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: 58K Golgi Protein purified from rat liver.

Isotype: IgG1

Information d'application

Indications d'application:

Positive Control: HeLa or HepG2 cells. Human kidney or liver tissue.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur FTCD

Antigène: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Autre désignation: FTCD (FTCD Produits)

Synonymes: anticorps LCHC1, anticorps FTCD, anticorps wu:fp37b11, anticorps zgc:63647, anticorps formimidoyltransferase cyclodeaminase, anticorps formiminotransferase cyclodeaminase, anticorps formiminotransferase-cyclodeaminase, anticorps formimidoyltransferase cyclodeaminase L homeolog, anticorps FTCD, anticorps Ftcd, anticorps ftcd, anticorps DP2350, anticorps Cbei_0990, anticorps TRQ2_1223, anticorps GAU_0899, anticorps ftcd.L

Sujet: Formimidoyltetrahydrofolate cyclodeaminase, Formiminotetrahydrofolate cyclodeaminase, Formiminotransferase cyclodeaminase, Glutamate formiminotransferase, Glutamate formyltransferase, LCHC1,FTCD / 58K Golgi Protein
Cellular localisation: Cytoplasm. Golgi apparatus.

Poids moléculaire: 59kDa

ID gène: 10841, 415846

UniProt: O95954