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CKM anticorps

Cet anticorps anti-CKM est un anticorps Souris Monoclonal détectant CKM dans ELISA et Coat. Adapté pour Humain.
N° du produit ABIN7126222

Aperçu rapide pour CKM anticorps (ABIN7126222)

Antigène

Voir toutes CKM Anticorps
CKM (Creatine Kinase, Muscle (CKM))

Reactivité

  • 106
  • 61
  • 45
  • 18
  • 9
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 111
  • 29
  • 13
  • 2
  • 1
Souris

Clonalité

  • 125
  • 30
Monoclonal

Conjugué

  • 82
  • 23
  • 13
  • 8
  • 7
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CKM est non-conjugé

Application

  • 119
  • 70
  • 63
  • 39
  • 31
  • 18
  • 13
  • 13
  • 10
  • 9
  • 8
  • 7
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Coating (Coat)
  • Specificité

    T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant full-length CKM protein

    Isotype

    IgG2a
  • Indications d'application

    Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: Human heart tissue. Skeletal muscle lysate.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    CKM (Creatine Kinase, Muscle (CKM))

    Autre désignation

    CKM

    Sujet

    CKM, CKMM, Creatine kinase M, Creatine kinase M chain, Creatine kinase M type, Creatine kinase M-type, Creatine kinase muscle, Creatine kinase, muscle type, M-CK, MCK, Muscle creatine kinase,Creatine Kinase MM
    Cellular localisation: Cytoplasm

    Poids moléculaire

    43kDa

    ID gène

    1158, 334347

    UniProt

    P06732
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