LRG1 anticorps (AA 30-180)

N° du produit ABIN7126226

Cet anticorps Souris Monoclonal détecte spécifiquement LRG1 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour LRG1 anticorps (AA 30-180) (ABIN7126226)

Antigène: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRG1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-LRG1 anticorps

Épitope: AA 30-180

Specificité: LRG1 (leucine-rich i±2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa 30-180) of human LRG1 protein (exact sequence is proprietary)

Isotype: IgG2

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver, pancreas or breast.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur LRG1

Antigène: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Autre désignation: LRG1

Sujet: 1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, Leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG1,LRG1 / Leucine Rich alpha-2-glycoprotein 1
Cellular localisation: Secreted.

Poids moléculaire: 38kDa

ID gène: 116844, 655559

UniProt: P02750

Pathways: Brown Fat Cell Differentiation