Recombinant CNN1 anticorps (C-Term)
Aperçu rapide pour Recombinant CNN1 anticorps (C-Term) (ABIN7126242)
Antigène
Voir toutes CNN1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- Recombinant Calponin-1 (Smooth Muscle Marker) Antibody
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Specificité
- Calponin a 33 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions. The antibody has been found in tissue extracts from smooth muscle, but not in fibroblast extracts.
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Réactivité croisée (Details)
- Human.
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Purification
- 200ug/ml of Ab purified by Protein A/G.
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Immunogène
- Synthetic peptide corresponding to residues on the C-terminus of human Calponin was used as an immunogen
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Isotype
- IgG, kappa
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Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: K562 cells. Myoepithelial cells in breast ducts or leiomyosarcoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- CNN1 (Calponin 1 (CNN1))
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Autre désignation
- CNN1
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Sujet
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Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC
K562 cells. Myoepithelial cells in breast ducts or leiomyosarcoma.
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Poids moléculaire
- 33kDa
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ID gène
- 1264, 465929
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UniProt
- P51911
Antigène
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