DAXX anticorps
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- Antigène Voir toutes DAXX Anticorps
- DAXX (Death-Domain Associated Protein (DAXX))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DAXX est non-conjugé
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificité
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
- Réactivité croisée (Details)
- Human
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human DAXX protein
- Isotype
- IgG2b
- Top Product
- Discover our top product DAXX Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- DAXX (Death-Domain Associated Protein (DAXX))
- Autre désignation
- DAXX (DAXX Produits)
- Synonymes
- anticorps BING2, anticorps DAP6, anticorps EAP1, anticorps LOC100226911, anticorps daxx, anticorps si:dz179b20.7, anticorps wu:fd15c03, anticorps death domain associated protein, anticorps Fas death domain-associated protein, anticorps 28S ribosomal protein S29, mitochondrial, anticorps death-domain associated protein, anticorps death-associated protein 6 L homeolog, anticorps DAXX, anticorps Daxx, anticorps LOC100226911, anticorps daxx.L, anticorps daxx
- Sujet
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DAP6, EAP1, BING2, SMIM40,DAXX
Cellular localisation: Nucleus. Cytosol. - Poids moléculaire
- 81.37kDa
- ID gène
- 1616, 336916
- UniProt
- Q9UER7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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