AKR1C1 anticorps

N° du produit ABIN7126291

Cet anticorps anti-AKR1C1 Monoclonal Souris (Clone CPTC-AKR1C1-2) (ABIN7126291) détecte spécifiquement AKR1C1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AKR1C1 anticorps (ABIN7126291)

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AKR1C1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CPTC-AKR1C1-2

Détail du produit anti-AKR1C1 anticorps

Fonction: Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody

Specificité: DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length AKR1C1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 or A549 cells. Human liver or stomach tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur AKR1C1

Antigène: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Autre désignation: AKR1C1

Sujet:

2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase

HepG2 or A549 cells. Human liver or stomach tissue.

Poids moléculaire: 37kDa

ID gène: 1645, 460260

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process