EIF4A2 anticorps

N° du produit ABIN7126324

Cet anticorps anti-EIF4A2 est un anticorps Souris Monoclonal détectant EIF4A2 dans ELISA et Coat. Adapté pour Humain.

Aperçu rapide pour EIF4A2 anticorps (ABIN7126324)

Antigène: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4A2 est non-conjugé

Application: ELISA, Coating (Coat)

Détail du produit anti-EIF4A2 anticorps

Specificité: Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a5'-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B, the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5' cap, eIF4A (I, II) are bidirectional RNA helicases, and eIF4G (I, II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.

Réactivité croisée (Details): Human. Predicted to work in Chick, Mouse, Rat, Xenopus and Zebrafish.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human EIF4A2 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur EIF4A2

Antigène: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Autre désignation: EIF4A2

Sujet: ATP dependent RNA helicase eIF4A 2, BM-010, DDX2B, EIF4F, eukaryotic translation initiation factor 4A isoform 2, N-terminally processed,EIF4A2 (Eukaryotic Initiation Factor 4A-II)
Cellular localisation: Nucleus.

Poids moléculaire: 46kDa

ID gène: 1974

UniProt: Q14240