ETS2 anticorps

N° du produit ABIN7126356

L’anticorps anti-ETS2 Monoclonal Souris est utilisé pour la détection de ETS2 dans des échantillons de Humain. Il a été validé pour ELISA, IF et FACS.

Aperçu rapide pour ETS2 anticorps (ABIN7126356)

Antigène: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ETS2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ETS2-1D9

Détail du produit anti-ETS2 anticorps

Fonction: ETS2 (Transcription Factor) Antibody

Specificité: ETS2 (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human ETS2 protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Optimal dilution for a specific application should be determined.

Positive_Control: Human thymus, lung or cerebellum.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur ETS2

Antigène: ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

Autre désignation: ETS2

Sujet:

C ets 2 protein, ETS2, ETS2IT1, Oncogene ETS2, Protein C-ets-2, v ets avian erythroblastosis virus E2 oncogene homolog 2, V ets avian erythroblastosis virus E26 oncogene homolog 2

Human thymus, lung or cerebellum.

Poids moléculaire: 52kDa

ID gène: 2114, 644231

UniProt: P15036

Pathways: EGFR Signaling Pathway, Myometrial Relaxation and Contraction