FOXL1 anticorps (AA 104-258)

N° du produit ABIN7126396

Détail du produit anti-FOXL1 anticorps

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Épitope: AA 104-258

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXL1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)

Specificité: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyer's patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

Réactivité croisée (Details): Human. Predicted to react in Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur FOXL1

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Autre désignation: FOXL1 (FOXL1 Produits)

Synonymes: anticorps zgc:63595, anticorps FOXL1, anticorps fkh6, anticorps fkhl11, anticorps freac7, anticorps CG1132, anticorps Dmel\\CG1132, anticorps Dmfd2, anticorps FD2, anticorps FoxL1, anticorps fd2, anticorps Foxl1, anticorps FKH6, anticorps FKHL11, anticorps FREAC7, anticorps Fkh6, anticorps fkh-6, anticorps forkhead box L1, anticorps forkhead domain 64A, anticorps forkhead transcription factor L1, anticorps forkhead box L1 transcription factor, anticorps foxl1, anticorps FOXL1, anticorps fd64A, anticorps LOC579718, anticorps Foxl1

Sujet: FKHL10, FREAC6, JFJ-3, FKH6, FKH11, Forkhead box protein L1, Forkhead related transcription factor, FREAC7,FOXL1 / Forkhead Box Protein L1 (Transcription Factor)
Cellular localisation: Nucleus.

Poids moléculaire: 36-41kDa

ID gène: 2299, 87236

UniProt: Q12951