GATA3 anticorps
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- Antigène Voir toutes GATA3 Anticorps
- GATA3 (GATA Binding Protein 3 (GATA3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GATA3 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50 kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67 % of urothelial Carcinomas, but none of prostate or renal carcinomas.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human GATA-3 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product GATA3 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human breast or urothelial carcinoma tissue.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- GATA3 (GATA Binding Protein 3 (GATA3))
- Autre désignation
- GATA3 (GATA3 Produits)
- Synonymes
- anticorps HDR, anticorps HDRS, anticorps Gata-3, anticorps jal, anticorps cb550, anticorps gta3, anticorps GATA-3, anticorps XGATA3, anticorps xgata-3, anticorps hdr, anticorps xGATA-3, anticorps GATA3, anticorps GATA transcription factor 3, anticorps T4L20.260, anticorps T4L20_260, anticorps gata3, anticorps ZH-DR, anticorps zgc:103531, anticorps GATA binding protein 3, anticorps GATA binding protein 3 S homeolog, anticorps GATA transcription factor 3, anticorps amidase, anticorps putative amidase, anticorps GATA-binding protein 3, anticorps hematopoietic death receptor, anticorps GATA3, anticorps Gata3, anticorps gata3, anticorps gata3.S, anticorps gatA3, anticorps hdr
- Sujet
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GATA binding protein-3, GATA-binding factor 3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Center) (Breast and Urothelial Marker)
Cellular localisation: Nuclear - Poids moléculaire
- 50kDa
- ID gène
- 2625, 524134
- UniProt
- P23771
- Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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