GCLM anticorps (Regulatory Subunit)

N° du produit ABIN7126478

Cet anticorps Souris Monoclonal détecte spécifiquement GCLM dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GCLM anticorps (Regulatory Subunit) (ABIN7126478)

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCLM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CPTC-GCLM-1

Détail du produit anti-GCLM anticorps

Épitope: Regulatory Subunit

Fonction: Glutamate-Cysteine Ligase Regulatory Subunit Antibody

Specificité: GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length GCLM protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: A549, HepG2 or HeLa cell lysates. Human muscle and liver tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GCLM

Antigène: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Autre désignation: GCLM

Sujet:

GCLM Antibody, Gamma-ECS regulatory subunit Antibody, GLCLR Antibody, GCS light chain Antibody, GSC light chain Antibody

A549, HepG2 or HeLa cell lysates. Human muscle and liver tissue.

Poids moléculaire: 31kDa

ID gène: 2730, 315562

UniProt: P48507