CD235a/GYPA anticorps
Aperçu rapide pour CD235a/GYPA anticorps (ABIN7126498)
Antigène
Voir toutes CD235a/GYPA (GYPA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
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Réactivité croisée (Details)
- Human. Others-not tested.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Human erythrocytes treated with neuraminidase
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Isotype
- IgG2a
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Indications d'application
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Known_Application: Flow Cytometry (0.5-1 μg/million cells), ,Immunofluorescence (0.5-1 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Erythrocytes
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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Autre désignation
- GYPA
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Sujet
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Blood group--MN locus, GPA, GPErik, GpMiIII, GPSAT, GYPA, MN sialoglycoprotein, MNS, PAS2, Sialoglycoprotein alpha,Glycophorin A / CD235a (Erythrocyte Marker)
Cellular localisation: Cell Surface -
Poids moléculaire
- 39kDa
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ID gène
- 2993, 2994
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UniProt
- P02724
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Pathways
- Maintenance of Protein Location
Antigène
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