Apolipoprotein D anticorps (AA 21-119)

N° du produit ABIN7126542

Détail du produit anti-Apolipoprotein D anticorps

Antigène: Apolipoprotein D (APOD)

Épitope: AA 21-119

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Apolipoprotein D est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human recombinant APOD protein fragment (around aa21-119) (exact sequence is proprietary)

Isotype: IgG2

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver, kidney or spleen.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Apolipoprotein D

Antigène: Apolipoprotein D (APOD)

Autre désignation: APOD (APOD Produits)

Synonymes: anticorps APOD, anticorps apod, anticorps zgc:153593, anticorps AOPDGN, anticorps Apo-D, anticorps lipocalin, anticorps apolipoprotein D, anticorps apolipoprotein Da, duplicate 1, anticorps APOD, anticorps CpipJ_CPIJ006492, anticorps CpipJ_CPIJ017615, anticorps CpipJ_CPIJ020105, anticorps apod, anticorps apoda.1, anticorps Apod

Sujet: APO-D protein,Apolipoprotein D / APO-D
Cellular localisation: Secreted.

Poids moléculaire: 30kDa

ID gène: 347, 522555

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling