Recombinant LHB anticorps

N° du produit ABIN7126642

Cet anticorps anti-LHB est un anticorps Souris Monoclonal détectant LHB dans IHC (f). Adapté pour Humain.

Aperçu rapide pour Recombinant LHB anticorps (ABIN7126642)

Antigène: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHB est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-LHB anticorps

Specificité: LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human LHB protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Anterior Pituitary

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur LHB

Antigène: LHB (Luteinizing Hormone beta Polypeptide (LHB))

Autre désignation: LHB

Classe de substances: Hormone

Sujet: ChorionicGonadotropin, Betapolypeptide 4 (CGB4), hLHB, Interstitial cell stimulating hormone beta chain, Leutropin, LH-B, LHB, LSH-B, LSH-beta, Luteinizing hormone beta polypeptide, Lutropin beta chain,LH-beta (Luteinizing Hormone-beta)
Cellular localisation: Cytoplasm.Secreted.

Poids moléculaire: 22kDa

ID gène: 3972, 154704

UniProt: P01229

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process