Recombinant TACSTD2 anticorps (AA 31-274)
Aperçu rapide pour Recombinant TACSTD2 anticorps (AA 31-274) (ABIN7126655)
Antigène
Voir toutes TACSTD2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 31-274
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Fonction
- Recombinant TACSTD2 / TROP2 (Epithelial Marker) Antibody
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Specificité
- TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
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Réactivité croisée (Details)
- Human.
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Purification
- 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.
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Immunogène
- Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HT29 cells. Human breast or colon carcinoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
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Autre désignation
- TACSTD2
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Sujet
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Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)
A-431, MCF7, HT29 cells. Human Skin or breast or colon carcinoma.
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Poids moléculaire
- 40kDa
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ID gène
- 4070, 23582
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UniProt
- P09758
Antigène
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