SMAD9 anticorps

N° du produit ABIN7126668

L’anticorps Souris Monoclonal anti-SMAD9 a été validé pour IF et FACS. Il convient pour détecter SMAD9 dans des échantillons de Humain.

Aperçu rapide pour SMAD9 anticorps (ABIN7126668)

Antigène: SMAD9 (SMAD Family Member 9 (SMAD9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD9 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-SMAD9 anticorps

Specificité: Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFi²/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFi² and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFi² signaling by interfering with TGFi²-mediated phosphorylation of other Smad family members.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human SMAD9 protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, U87 or Ramos cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SMAD9

Antigène: SMAD9 (SMAD Family Member 9 (SMAD9))

Autre désignation: SMAD9

Sujet: MAD homolog 9, Madh6, Mothers against decapentaplegic homolog 9, Mothers against DPP homolog 9, SMAD family member 9, SMAD, mothers against DPP homolog 9 (Drosophila), SMAD8A, SMAD8B, Smad9,SMAD9
Cellular localisation: Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4.

Poids moléculaire: 52.4kDa

ID gène: 4093, 123119

UniProt: O15198