SMAD9 anticorps
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- Antigène Voir toutes SMAD9 Anticorps
- SMAD9 (SMAD Family Member 9 (SMAD9))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SMAD9 est non-conjugé
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificité
- Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFi²/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFi² and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFi² signaling by interfering with TGFi²-mediated phosphorylation of other Smad family members.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human SMAD9 protein
- Isotype
- IgG1
- Top Product
- Discover our top product SMAD9 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or Ramos cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- SMAD9 (SMAD Family Member 9 (SMAD9))
- Autre désignation
- SMAD9 (SMAD9 Produits)
- Synonymes
- anticorps SMAD8, anticorps MADH6, anticorps MADH9, anticorps PPH2, anticorps SMAD8A, anticorps SMAD8B, anticorps Madh8, anticorps Madh9, anticorps Smad8, anticorps SMAD family member 9, anticorps SMAD9, anticorps smad9, anticorps Smad9
- Sujet
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MAD homolog 9, Madh6, Mothers against decapentaplegic homolog 9, Mothers against DPP homolog 9, SMAD family member 9, SMAD, mothers against DPP homolog 9 (Drosophila), SMAD8A, SMAD8B, Smad9,SMAD9
Cellular localisation: Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. - Poids moléculaire
- 52.4kDa
- ID gène
- 4093, 123119
- UniProt
- O15198
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