PBX2 anticorps

N° du produit ABIN7126762

Cet anticorps anti-PBX2 est un anticorps Souris Monoclonal détectant PBX2 dans ELISA, IF, IP, BP, Coat et FACS. Adapté pour Humain.

Aperçu rapide pour PBX2 anticorps (ABIN7126762)

Antigène: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PBX2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Blocking Peptide (BP), Coating (Coat), Flow Cytometry (FACS)

Détail du produit anti-PBX2 anticorps

Specificité: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human PBX2 protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Expressed in all tissues except in cells of the B and T lineage.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PBX2

Antigène: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Autre désignation: PBX2

Sujet: G17, Homeobox protein PBX2, HOX12, PBX2MHC, pre B cell leukemia homeobox 2, Pre-B-cell leukemia transcription factor 2, Protein G17,PBX2 / PRL (Transcription Factor)
Cellular localisation: Nucleus.

Poids moléculaire: 46kDa

ID gène: 5089, 557097

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development