PLP1 anticorps (AA 272-277)

N° du produit ABIN7126797

L’anticorps Souris Monoclonal anti-PLP1 a été validé pour IHC (f). Il convient pour détecter PLP1 dans des échantillons de Humain.

Aperçu rapide pour PLP1 anticorps (AA 272-277) (ABIN7126797)

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLP1 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-PLP1 anticorps

Épitope: AA 272-277

Specificité: Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.

Réactivité croisée (Details): Human, Mouse, Rat, Tenerife Lizard and Cow.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human brain tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PLP1

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Autre désignation: PLP1

Sujet: Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20,Proteolipid Protein / Myelin PLP
Cellular localisation: Membrane

Poids moléculaire: 23-25kDa

ID gène: 5354, 1787

UniProt: P60201