PRMT7 anticorps

N° du produit ABIN7126811

Cet anticorps Souris Monoclonal détecte spécifiquement PRMT7 dans WB, IF, IP et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour PRMT7 anticorps (ABIN7126811)

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRMT7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Détail du produit anti-PRMT7 anticorps

Specificité: Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

Réactivité croisée (Details): Human. Predicted to react with Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human PRMT7 protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, MCF7 or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur PRMT7

Antigène: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Autre désignation: PRMT7

Sujet: [Myelin basic protein]-arginine N-methyltransferase PRMT7, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7,PRMT7
Cellular localisation: Nucleus. Nucleoplasm. Cytoplasm.

Poids moléculaire: 78.46kDa

ID gène: 54496, 640229

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization