TRIM27 anticorps

N° du produit ABIN7126897

Détail du produit anti-TRIM27 anticorps

Antigène: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM27 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.

Réactivité croisée (Details): Human. Predicted to react with Mouse and Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human TRIM27 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, U87 or Raji cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TRIM27

Antigène: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Autre désignation: TRIM27 (TRIM27 Produits)

Synonymes: anticorps RFP, anticorps RNF76, anticorps AW538890, anticorps Gm19403, anticorps Rfp, anticorps TRIM27, anticorps Rfp1, anticorps tripartite motif containing 27, anticorps tripartite motif-containing 27, anticorps TRIM27, anticorps Trim27

Sujet: AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP,TRIM27
Cellular localisation: Nucleus. Cytoplasm. Nucleus > PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies.

Poids moléculaire: 58.49kDa

ID gène: 5987, 440382

UniProt: P14373