Retinoid X Receptor beta anticorps

N° du produit ABIN7126907

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoid X Receptor beta dans WB, FACS, IF et IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour Retinoid X Receptor beta anticorps (ABIN7126907)

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor beta est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-Retinoid X Receptor beta anticorps

Specificité: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARi±, RARi² and RARi³, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human RXRB protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Retinoid X Receptor beta

Antigène: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Autre désignation: RXRB

Sujet: DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta,RXRB
Cellular localisation: Nucleus.

Poids moléculaire: 50-54kDa

ID gène: 6257, 388034

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway