Retinoid X Receptor gamma anticorps

N° du produit ABIN7126909

Cet anticorps anti-Retinoid X Receptor gamma est un anticorps Souris Monoclonal détectant Retinoid X Receptor gamma dans ELISA, IF, IP, Coat et FACS. Adapté pour Humain.

Aperçu rapide pour Retinoid X Receptor gamma anticorps (ABIN7126909)

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor gamma est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)

Détail du produit anti-Retinoid X Receptor gamma anticorps

Specificité: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRi±, RXRi² and RXRi³, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

Réactivité croisée (Details): Human. Predicted to react in Mouse, Rat and Chick.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human RXRG protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: SK-MEL-30, U-2 OS or HeLa cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Retinoid X Receptor gamma

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Autre désignation: RXRG

Sujet: Nuclear receptor subfamily 2 group B member 3 (NR2B3), Retinoic X receptor gamma (RXRG), Retinoic acid receptor RXR gamma, RXR gamma, RXRC,RXRG / NR2B3 (Transcription Factor)
Cellular localisation: Nucleus > Nucleoplasm > Nuclear bodies.

Poids moléculaire: 50.87kDa

ID gène: 6258, 26550

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway