SCXA anticorps

N° du produit ABIN7126933

Détail du produit anti-SCXA anticorps

Antigène: SCXA (Scleraxis (SCXA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SCXA est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité: Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human SCXA protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SCXA

Antigène: SCXA (Scleraxis (SCXA))

Autre désignation: SCX (SCXA Produits)

Synonymes: anticorps BB114693, anticorps Bhlha41, anticorps Scl, anticorps SCX, anticorps bHLHa48, anticorps scleraxis, anticorps scleraxis bHLH transcription factor, anticorps Scx, anticorps SCX

Sujet: Basic helix loop helix transcription factor scleraxis, bHLHa41, bHLHa48, Class A basic helix-loop-helix protein 41, Class A basic helix-loop-helix protein 48, scleraxis homolog A, SCX, SCXB,SCXA
Cellular localisation: Nucleus.

Poids moléculaire: 22kDa

ID gène: 642658, 723088

UniProt: Q7RTU7