MLX anticorps

N° du produit ABIN7126996

L’anticorps Souris Monoclonal anti-MLX a été validé pour WB, IF et FACS. Il convient pour détecter MLX dans des échantillons de Humain.

Aperçu rapide pour MLX anticorps (ABIN7126996)

Antigène: MLX (MAX-Like Protein X (MLX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-MLX anticorps

Specificité: Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad1, Mad3, Mad4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad1, Mad4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.

Réactivité croisée (Details): Human

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human MLX protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or MCF7 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur MLX

Antigène: MLX (MAX-Like Protein X (MLX))

Autre désignation: MLX

Sujet: BHLHd13, Class D basic helix-loop-helix protein 13, MAD7, Max-like bHLHZip protein, Max-like protein X, MLXIP, MONDOA, MXD7, Protein BigMax, Protein Mlx, Transcription factor-like protein 4 (TCFL4),MLX
Cellular localisation: Nucleus and cytoplasm.

Poids moléculaire: 30kDa

ID gène: 6945

UniProt: Q9UH92