TTR anticorps

N° du produit ABIN7127029

L’anticorps Souris Monoclonal anti-TTR a été validé pour WB et IHC (f). Il convient pour détecter TTR dans des échantillons de Humain.

Aperçu rapide pour TTR anticorps (ABIN7127029)

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-TTR anticorps

Specificité: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human full-length protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: Western Blot (2-4 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: TTR

Sujet: Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody,Transthyretin (Prealbumin)
Cellular localisation: Secreted. Cytoplasm.

Poids moléculaire: 15kDa

ID gène: 7276, 427202

UniProt: P02766

Pathways: Hormone Transport