NOC4L anticorps

N° du produit ABIN7127072

Cet anticorps anti-NOC4L est un anticorps Souris Monoclonal détectant NOC4L dans FACS et IF. Adapté pour Humain.

Aperçu rapide pour NOC4L anticorps (ABIN7127072)

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOC4L est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-NOC4L anticorps

Specificité: Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

Réactivité croisée (Details): Human

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human NOC4L protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or 293T cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur NOC4L

Antigène: NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Autre désignation: NOC4L

Sujet: NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein,Nucleolar complex-associated protein 4-like protein (NOC4L)
Cellular localisation: Nucleus.

Poids moléculaire: 58.4kDa

ID gène: 79050, 558536

UniProt: Q9BVI4