ZNF408 anticorps
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- Antigène Voir toutes ZNF408 Anticorps
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ZNF408 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificité
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human ZNF408 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product ZNF408 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
- Autre désignation
- ZNF408 (ZNF408 Produits)
- Synonymes
- anticorps Gm1011, anticorps zinc finger protein 408, anticorps ZNF408, anticorps Zfp408, anticorps Znf408, anticorps znf408
- Sujet
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (ZNF408),ZNF408 / PRDM17 (Transcription Factor)
Cellular localisation: Nucleus. - Poids moléculaire
- 118kDa
- ID gène
- 79797, 60300
- UniProt
- Q9H9D4
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